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Ellen Pompeo Dishes on Kissing Patrick Dempsey

Grey's Anatomy star opens up about life on one of TV's biggest shows.

It's a question for the ages: McDreamy or McSteamy?

On last night's Watch What Happens Live, Ellen Pompeo, one of the stars of ABC's long-running medical drama Grey's Anatomy, let Andy Cohen quiz her on her personal relationship with the show. Her pick: "McDreamy."

Pompeo also revealed Patrick Dempsey is a better kisser than Chris O'Donnell. When Andy asked her to explain her pick, Pompeo quickly responds, "We don't have that much time." There's always the after show, Ellen!

As far as which departed cast member Pompeo misses the most, she says, "T.R. [Knight] and Katy [Katherine Heigl] are kind of the same person, so T.R. and Katy." She adds, "They're a sandwich."

Which moment on the show was her least favorite? Pompeo picks the musical episode, which aired in 2011 to mixed reviews.

And lastly, who's a bigger bitch to work with: Katherine Heigl or Isaiah Washington? "Isaiah all the way," she says, laughing.

Watch Ellen Pompeo dish on Patrick Dempsey kisses and which former castmate she misses the most and tell us in the comments: who's your favorite Grey's Anatomy star?