The ladies pack for their upcoming girls’ weekend in Florida. Gretchen Rossi wishes that her boyfriend, Slade Smiley, was coming with her. It's shaping up to be the perfect girls’ weekend getaway, until Gretchen suspects that Alexis Bellino's husband, Jim, and Tamra Barney's husband, Simon, will not allow their wives to travel without them. Tamra, Simon, Gretchen and Lynne Curtin arrive at the hotel and meet Vicki for drinks. Everyone is shocked when Slade strolls in to surprise Gretchen. Vicki can’t hide her displeasure at yet another man crashing her girls' weekend.
Meanwhile, Alexis is still at home packing, planning to join the ladies a day late because she and Jim refuse to leave their three kids with nannies for that long. Alexis finally makes it to Florida and joins her new girlfriends for dinner. The conversation at dinner takes an uncomfortable turn when Vicki confronts Gretchen about why she is dating Slade. A divide also begins to form between Vicki and Tamra, who is torn between her husband and her friend.