During the After Show, Melissa Etheridge talks about her new album, “The Medicine Show,” and how it deals with themes of addiction in light of the opioid crisis.

Melissa Etheridge reveals that she once taught Brad Pitt how to fly fish in her swimming pool as he was preparing to audition for “A River Runs Through It.”

A viewer calls in to ask if Melissa Etheridge heard anything from Brad Pitt or Angelina Jolie about her original “Brangelina” song she first performed on #WWHL, and Chelsea Handler weighs in as well.

Chelsea Handler gives her take on the Kevin Hart Oscars debacle, saying she doesn’t think comedians should be held accountable for everything they’ve said in the past.

Chelsea Handler tells Andy Cohen that she doesn’t miss doing her show “Chelsea Lately,” saying she liked it in the beginning, but that the eight years she did the show “felt like 12.”