But can she twirl like Kenya?
NeNe, who has also had roles on Glee, the New Normal, and Celebrity Apprentice, will be teaming up with partner Tony Dovolani. Her partner was a season 15 all-stars champion with Melissa Rycroft.
She'll face some tough competition. Among this season's other 12 competitors: Full House star Candace Cameron Bure, pop singer Cody Simpson, actor-singer James Maslow, the Wonder Years' Danica McKellar, swimming legend Diana Nyad, television personality and comic Drew Carey, snowboarding champ Amy Purdy, NHL star Sean Avery, and actor Billy Dee Williams.
In another twist, Sochi Olympic stars Charlie White and Meryl Davis will also be competing—but the ice dancing partners will be facing off against each other.
For its latest season, producers have shaken up the format. Host Brooke Burke-Charvet has been replaced with Erin Andrews. And fans will be able to vote to switch celebrity contestants with their professional partners mid-season.
Of course, NeNe isn't the first Housewife to join DWTS. Lisa Vanderpump was featured in the line-up for Season 16, but was eliminated.
Do you think NeNe has what it takes to win Dancing With the Stars? Tell us in the comments.