But the mother to daughter Avery is leaning on her friends and family—and on Tuesday, she thanked them for keeping her in their thoughts.
"This has been the most difficult time in my life," she Tweeted. "But when I see so many messages of love & support, it gives me a much needed smile #Thankful"
Despite her personal turmoil, Ramona hasn't gone into hiding. Last week, she got her stress out by going to the gym and she tweeted excitement about watching the Super Bowl on Sunday (she's a Bruno Mars fan!).
She's also turned to inspirational books for some uplift and shared the following passage from philosopher C. JoyBell C.: "We can't be afraid of change. You may feel very secure in the pond that you are in, but if you never venture out of it, you will never know that there is such a thing as an ocean, a sea. Holding onto something that is good for you now, may be the very reason why you don't have something better."
Housewives across the country are chiming in with messages of love and support, including Kyle Richards and Dina Manzo. Castmate Carole Radziwill also sent her a gorgeous bouquet and Ramona shared a snap of the flowers online.
Send your messages to Ramona in the comments and watch a preview of the new RHONY below (premiering March 11 at 9/8c).